One dimensional migration of DNA in the presence of point particle traps

Authors

Sarah Johnson; Cristine Villagonzalo

Source

Proceedings of the 27th Samahang Pisika ng Pilipinas Physics Congress, Development Academy of the Philippines Convention Center, Tagaytay City, SPP-2009-071 (2009).

Abstract

This paper studies the one-dimensional motion of a DNA molecule through a microchannel with a series of point particle electric traps. The three particle molecule model uses three beads connected via harmonic springs in the presence of a Weeks Chandler-Andersen repulsive potential and a Brownian force. Using the stochastic fourth order Runge-Kutta method, the trajectory of the center of mass is observed as the field strengths were varied. System parameters are identified that can impede the flow of a DNA molecule.